Is cologuard just as good as a colonoscopy?
Matthew Cannon
Updated on January 11, 2026
No, the Cologuard test is not as effective as a colonoscopy. Detecting and removing polyps is critical to colon cancer prevention, and Cologuard only detects large precancerous polyps 42% of the time. A colonoscopy detects the same polyps 95% of the time and they are removed during the same procedure.
Can I use cologuard instead of a colonoscopy?
The majority of large precancerous polyps cannot be detected with Cologuard. This may give patients a false sense that they are preventing colon cancer by taking the Cologuard test. In short, there is no true replacement for a colonoscopy.Why is cologuard not recommended?
Cologuard is not as good at finding pre-cancerous polyps and, unlike colonoscopy, it can't remove them. According to the NEJM study, Cologuard misses more than 30 percent of polyps that will soon be cancer, and 57 percent of polyps that may become cancer.What do gastroenterologists think of cologuard?
I feel most gastroenterologists would agree Cologuard is a potent weapon in the armamentarium against colon cancer. The 92 percent sensitivity for CRC, and 69 percent sensitivity for detection adenomas with high grade dysplasia, make it the standard second line option, next to colonoscopy.Is cologuard good enough?
Just how good is Cologuard? Based on the one major study cited,(6) it is pretty darned good: Cologuard detected 92% of colorectal cancers and 42% of advanced polyps. As a comparison, the FIT test detected 74% of cancers and 24% of advanced polyps.Cologuard vs Colonoscopy (Pt. 1)
Is cologuard a waste of time?
Ninety-five percent of colon cancers begin as polyps. Cologuard is not as good at finding pre-cancerous polyps and, unlike colonoscopy, it can't remove them. According to the NEJM study, Cologuard misses more than 30 percent of polyps that will soon be cancer, and 57 percent of polyps that may become cancer.Does cologuard detect polyps?
Although the Cologuard test can detect signs of colorectal cancer or advanced colon polyps, it can't detect polyps in their earliest stages when they can be easily removed.Why are colonoscopies not recommended after age 75?
“There are risks involved with colonoscopy, such as bleeding and perforation of the colon, and also risks involved with the preparation, especially in older people,” Dr.Are colonoscopies recommended after age 80?
The guidelines: recommend screening for colorectal cancer using fecal occult blood testing, sigmoidoscopy, or colonoscopy in adults, beginning at age 50 years and continuing until age 75. recommend against routine screening for colorectal cancer in adults age 76 to 85 years.Does Medicare pay for cologuard?
Cologuard is covered by Medicare and Medicare Advantage with no co-pay or deductible for eligible patients ages 50-85.Who Cannot get Cologuard?
Cologuard may not be right for you if:You have a family history of colon cancer (one or more first-degree relatives diagnosed with colon or rectal cancer before the age of 60, or two or more first degree relatives diagnosed with colon or rectal cancer of any age)