Can I take naproxen and paracetamol together?
Andrew Mccoy
Updated on January 07, 2026
Do not take naproxen with ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs). But it's OK to take naproxen with paracetamol or co-codamol that you buy over the counter. This should just be for short periods of time.
co-codamol
Codeine/paracetamol, also known as codeine/acetaminophen and co-codamol, is a compound analgesic consisting of a combination of codeine phosphate and paracetamol (acetaminophen).
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How long after paracetamol can you take naproxen?
Wait at least four hours before you consider taking any more Paracetamol or Codeine. Leave 12 hours between Naproxen doses. Use the chart below to help you keep a record of the painkillers that you have taken. Enter the time, your level of pain and the number of tablets you took.Does naproxen work better with paracetamol?
Furthermore, the effect of the highest naproxen dose was not better than the effect of the lower naproxen dose (1.0 g daily) combined with paracetamol. The main finding was that treatment with naproxen and paracetamol is more effective than treatment with higher naproxen doses alone.What painkillers can you take with naproxen?
Paracetamol and opioid-type painkillers (such as codeine) are fine to use alongside Naproxen. It is also important to remember that cold-and-flu remedies can sometimes contain ibuprofen or aspirin, so you should avoid taking this while you are using Naproxen. The same goes for anti-inflammatory gels.What drugs should not be taken with naproxen?
Some products that may interact with this drug are: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), cidofovir, corticosteroids (such as prednisone), lithium, "water pills" (diuretics such as furosemide).Can I take ibuprofen and paracetamol together? - Common Health Questions | NHS
Can I take 2 naproxen 500mg at the same time?
Adults—At first, 750 milligrams (mg) (taken as one 750 mg or two 375 mg tablets) or 1000 mg (taken as two 500 mg tablets) once a day. Your doctor may adjust your dose as needed. However the dose is usually not more than 1500 mg (taken as two 750 mg or three 500 mg tablets) per day.Is naproxen stronger than ibuprofen?
This makes them effective at relieving pain and reducing inflammation, but there is a risk of stomach-related side effects. As far as effectiveness goes, a dose of 440mg naproxen is approximately equivalent to a dose of 400mg ibuprofen.Is naproxen a painkiller or muscle relaxer?
Is naproxen a muscle relaxer or pain killer? Naproxen is not technically a muscle relaxer; it is a pain medication and also helps with inflammation.Does naproxen make you sleepy?
Prescription naproxen oral tablets may cause drowsiness. You shouldn't drive, use machinery, or do other activities that require alertness until you know you can function normally. This drug can also cause other side effects.What is the strongest anti-inflammatory medication?
Research shows diclofenac is the strongest and most effective non-steroidal anti-inflammatory medicine available. 10 Diclofenec is sold under the prescription brand names Cambia, Cataflam, Zipsor, and Zorvolex. It is also available as a topical gel, Voltaren, which is available over the counter.What is better for arthritis ibuprofen or naproxen?
Conclusion: Over-the-counter doses of naproxen sodium (440/660 mg) and ibuprofen (1200 mg) effectively relieve pain in patients with mild to moderate OA of the knee. Naproxen sodium provided more effective pain relief for most variables compared with placebo, and for night pain compared with ibuprofen.What is better for back pain ibuprofen or naproxen?
Best for all day/night back pain relief: Naproxen (Aleve)It works by decreasing inflammation, similar to ibuprofen. But it lasts longer than ibuprofen.